On Genetics, Lung Developmental Biology, and Adult Lung Function
نویسندگان
چکیده
منابع مشابه
Lung function, genetics and ethnicity.
Professor Quanjer’s editorial makes several errors in reporting our views on ethnicity and lung function [1], views that had been fairly summarised by BRAUN et al. [2] in the paper on which the editorial comments. Among his more unfortunate assertions is that our conclusions are reminiscent of the racist views of Hoffman. As the purpose of the paper to which the editorial refers was precisely t...
متن کاملLung function, genetics and socioeconomic conditions.
It has long been known [1] that, when comparing subjects of the same age and height, African ancestry is associated with 12–20% smaller forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC) than European ancestry. Both smaller and larger differences have been reported in studies of other ethnic groups. This has led to numerous efforts to explain the underlying reason for these ...
متن کاملEffects of sirolimus on Lung function in patients with Lymphangioleiomyomatosis
Background: Lymphangioleiomyomatosis (LAM) is a progressive lungs disease that affects women at reproductive years. Sirolimus inhibits mammalian target of rapamycin (mTOR) and its administration in past studies was hopeful in treatment of patients with LAM. The aim of this study was to evaluate sirolimus therapy on lung function in LAM patients. Methods: We conducted a trial to evaluate the ef...
متن کاملcompactifications and function spaces on weighted semigruops
chapter one is devoted to a moderate discussion on preliminaries, according to our requirements. chapter two which is based on our work in (24) is devoted introducting weighted semigroups (s, w), and studying some famous function spaces on them, especially the relations between go (s, w) and other function speces are invesigated. in fact this chapter is a complement to (32). one of the main fea...
15 صفحه اولThe genetics and biology of KRAS in lung cancer
Mutational activation of KRAS is a common oncogenic event in lung cancer and other epithelial cancer types. Efforts to develop therapies that counteract the oncogenic effects of mutant KRAS have been largely unsuccessful, and cancers driven by mutant KRAS remain among the most refractory to available treatments. Studies undertaken over the past decades have produced a wealth of information rega...
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ژورنال
عنوان ژورنال: American Journal of Respiratory and Critical Care Medicine
سال: 2020
ISSN: 1073-449X,1535-4970
DOI: 10.1164/rccm.202006-2123ed